Having a passion for translational research and for finding cures for intractable conditions that cause human suffrage and death, I seek to translate fundamental mechanisms of biochemistry and energy metabolism into novel therapeutic approaches for the treatment of neurological conditions. A major research effort is the development of metabolism-based therapies that enable disease modification in epilepsy and after traumatic brain injury. I graduated at the University of Köln, Germany, in 1994 with a PhD in Biochemistry. In 2005 I received the venia legendi (Habilitation) in Cellular Pharmacology from the University of Zurich, Switzerland, for my work on cell-based adenosine augmentation therapies for epilepsy. Over the past 25 years I have maintained a rigorous research program on translational adenosine research and have been continuously NIH funded since 2008. I have published around 200 papers with an h-index of 66 and have delivered over 160 invited lectures worldwide.

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Research Interests:

• The biochemistry and epigenetics of epilepsy
• Focal adenosine-augmentation therapies to treat epilepsy
• Therapies for epilepsy prevention
• Brain regeneration after traumatic brain injury and stroke
• Comorbidities in Neurology
• The adenosine hypothesis of schizophrenia
• Role of adenosine in cancer
• Metabolic therapies